Advertisement
Review Article| Volume 55, P35-48, September 2021

Malignant Bowel Obstruction

      Malignant bowel obstruction (MBO) is a frequent and often lethal condition affecting patients with advanced gastrointestinal cancers.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Advances in Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Anthony T.
        • Baron T.
        • Mercadante S.
        • et al.
        Report of the clinical protocol committee: development of randomized trials for malignant bowel obstruction.
        J Pain Symptom Manage. 2007; 34: S49-S59
        • Laval G.
        • Marcelin-Benazech B.
        • Guirimand F.
        • et al.
        Recommendations for Bowel Obstruction With Peritoneal Carcinomatosis.
        J Pain Symptom Manage. 2014; 48: 75-91
        • Tuca A.
        • Guell E.
        • Martinez-Losada E.
        • et al.
        Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution.
        Cancer Manag Res. 2012; 4: 159
      1. Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review for clinical practice. Belg J Med Oncol 2019;13(4):123–8.

        • Roses R.E.
        • Folkert I.W.
        • Krouse R.S.
        Malignant bowel obstruction: reappraising the value of surgery.
        Surg Oncol Clin N Am. 2018; 27: 705-715
      2. al KY et. Surgical and Conservative Management of Malignant Bowel Obstruction: Outcome and Prognostic Factors | EndNote Click.
        (Available at:) (Accessed December 4, 2020)
        • Bento J.H.
        • Bianchi E.T.
        • Tustumi F.
        • et al.
        Surgical management of malignant intestinal obstruction: outcome and prognostic factors.
        Chirurgia (Bucur). 2019; 114: 343-351
        • Ripamonti C.I.
        • Easson A.M.
        • Gerdes H.
        Management of malignant bowel obstruction.
        Eur J Cancer. 2008; 44: 1105-1115
        • Ferrell B.R.
        • Temel J.S.
        • Temin S.
        • et al.
        Integration of palliative care into standard oncology care: american society of clinical oncology clinical practice guideline update.
        J Clin Oncol. 2017; 35: 96-112
        • Bakitas M.A.
        • Tosteson T.D.
        • Li Z.
        • et al.
        Early versus delayed initiation of concurrent palliative oncology care: patient outcomes in the ENABLE III randomized controlled trial.
        J Clin Oncol. 2015; 33: 1438-1445
        • Haun M.W.
        • Estel S.
        • Rücker G.
        • et al.
        Early palliative care for adults with advanced cancer.
        Cochrane Database Syst Rev. 2017; (CD011129)
        • Dionne-Odom J.N.
        • Azuero A.
        • Lyons K.D.
        • et al.
        Benefits of early versus delayed palliative care to informal family caregivers of patients with advanced cancer: outcomes from the ENABLE III randomized controlled trial.
        J Clin Oncol. 2015; 33: 1446-1452
        • Brinkman-Stoppelenburg A.
        • Rietjens J.A.C.
        • van der Heide A.
        The effects of advance care planning on end-of-life care: a systematic review.
        Palliat Med. 2014; 28: 1000-1025
        • Kubi B.
        • Istl A.C.
        • Lee K.T.
        • et al.
        Advance Care Planning in Cancer: Patient Preferences for Personnel and Timing.
        JCO Oncol Pract. 2020; 16: e875-e883
        • Teno J.M.
        • Gruneir A.
        • Schwartz Z.
        • et al.
        Association between advance directives and quality of end-of-life care: a national study.
        J Am Geriatr Soc. 2007; 55: 189-194
        • Khandelwal N.
        • Kross E.K.
        • Engelberg R.A.
        • et al.
        Estimating the effect of palliative care interventions and advance care planning on ICU utilization: a systematic review.
        Crit Care Med. 2015; 43: 1102-1111
        • Mor V.
        • Laliberte L.
        • Morris J.N.
        • et al.
        The Karnofsky performance status scale: An examination of its reliability and validity in a research setting.
        Cancer. 1984; 53 (Available at:): 2002-2007https://doi.org/10.1002/1097-0142(19840501)53:9<2002::AID-CNCR2820530933>3.0.CO;2-W
        • Allard P.
        • Dionne A.
        • Potvin D.
        Factors associated with length of survival among 1081 terminally ill cancer patients.
        J Palliat Care. 1995; 11: 20-24
      3. Jin H( W and JO. Performance Status in Patients With Cancer | EndNote Click.
        (Available at:) (Accessed December 22, 2020)
        • Yates J.W.
        • Chalmer B.
        • McKegney F.P.
        Evaluation of patients with advanced cancer using the karnofsky performance status.
        Cancer. 1980; 45 (Available at:): 2220-2224https://doi.org/10.1002/1097-0142(19800415)45:8<2220::AID-CNCR2820450835>3.0.CO;2-Q
        • Hwang S.S.
        • Scott C.B.
        • Chang V.T.
        • et al.
        Prediction of Survival for Advanced Cancer Patients by Recursive Partitioning Analysis: Role of Karnofsky Performance Status, Quality of Life, and Symptom Distress.
        Cancer Invest. 2004; 22: 678-687
      4. The publication of The Art and Science of Palliative Medicine - Annals of Palliative Medicine.
        (Available at:) (Accessed December 7, 2020)
        • Krouse R.S.
        • McCahill L.E.
        • Easson A.M.
        • et al.
        When the Sun Can Set on an Unoperated Bowel Obstruction: Management of Malignant Bowel Obstruction.
        J Am Coll Surg. 2002; 195: 12
        • Miccò M.
        • Sbarra M.
        • Gui B.
        • et al.
        Prognostic CT findings of malignant bowel obstruction in patients with advanced ovarian cancer.
        Tumori. 2020; 106: 149-154
        • Filippone A.
        • Cianci R.
        • Storto M.L.
        Bowel obstruction: comparison between multidetector-row CT axial and coronal planes.
        Abdom Imaging. 2007; 32: 310-316
        • Maglinte D.D.T.
        • Kelvin F.M.
        • Sandrasegaran K.
        • et al.
        Radiology of small bowel obstruction: contemporary approach and controversies.
        Abdom Imaging. 2005; 30: 160-178
        • Silva A.C.
        • Pimenta M.
        • Guimaraes L.S.
        Small Bowel Obstruction: What to Look For.
        RadioGraphics. 2009; 29: 423-439
        • Abbas S.
        • Bissett I.P.
        • Parry B.R.
        Oral water soluble contrast for the management of adhesive small bowel obstruction.
        Cochrane Database Syst Rev. 2007; 2007https://doi.org/10.1002/14651858.CD004651.pub3
        • Khasawneh M.A.
        • Eiken P.W.
        • Srvantstyan B.
        • et al.
        Use of the Gastrografin challenge in patients with a history of abdominal or pelvic malignancy.
        Surgery. 2013; 154 ([discussion: 775–6]): 769-775
        • Syrmis W.
        • Richard R.
        • Jenkins-Marsh S.
        • et al.
        Oral water soluble contrast for malignant bowel obstruction.
        Cochrane Database Syst Rev. 2018; 2018https://doi.org/10.1002/14651858.CD012014.pub2
        • Dolan E.A.
        Malignant Bowel Obstruction: A Review of Current Treatment Strategies.
        Am J Hosp Palliat Care. 2011; 28: 576-582
      5. al NM et. Health-related quality of life in patients with inoperable malignant bowel obstruction: secondary outcome from a double-blind, parallel, placebo-controlled randomised trial of octreotide | EndNote Click.
        (Available at:) (Accessed December 7, 2020)
        • Miller G.
        • Boman J.
        • Shrier I.
        • et al.
        Small-bowel obstruction secondary to malignant disease: an 11-year audit.
        Can J Surg. 2000; 43: 353-358
        • Blair S.L.
        • Chu D.Z.J.
        • Schwarz R.E.
        Outcome of palliative operations for malignant bowel obstruction in patients with peritoneal carcinomatosis from nongynecological cancer.
        Ann Surg Oncol. 2001; 8: 632-637
        • Hsu K.
        • Prommer E.
        • Murphy M.C.
        • et al.
        Pharmacologic management of malignant bowel obstruction: when surgery is not an option.
        J Hosp Med. 2019; 14: 367-373
        • MacDougall M.R.
        • Sharma S.
        Physiology, Chemoreceptor Trigger Zone.
        in: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL)2020 (Jan PMID: 30725818)
        • Babic T.
        • Browning K.N.
        The role of vagal neurocircuits in the regulation of nausea and vomiting.
        Eur J Pharmacol. 2014; 722: 38-47
        • Walsh D.
        • Davis M.
        • Ripamonti C.
        • et al.
        2016 Updated MASCC/ESMO consensus recommendations: Management of nausea and vomiting in advanced cancer.
        Support Care Cancer. 2017; 25: 333-340
        • Mercadante S.
        • Ferrera P.
        • Villari P.
        • et al.
        Aggressive pharmacological treatment for reversing malignant bowel obstruction.
        J Pain Symptom Manage. 2004; 28: 412-416
      6. al AJF et. Management of Malignant Bowel Obstruction Associated With GI Cancers | EndNote Click.
        (Available at:) (Accessed December 8, 2020)
        • Halley A.
        A systematic review of the use of anti-secretory medicines for the control of gastrointestinal symptoms in patients with malignant bowel obstruction.
        Palliat Med. 2016; 30: S8-S9
        • Magee C.
        Octreotide in the management of nausea and vomiting secondary to inoperable malignant bowel obstruction: a systematic review.
        Palliat Med. 2014; 28
      7. D. C. Currow - Double-Blind, Placebo-Controlled, Randomized Trial of Octreotide in Malignant Bowel Obstruction.
        (Available at:) (Accessed December 19, 2020)
        • Laval G.
        • Rousselot H.
        • Toussaint-Martel S.
        • et al.
        SALTO: a randomized, multicenter study assessing octreotide LAR in inoperable bowel obstruction.
        Bull Cancer. 2012; 99: E1-E9
        • Currow D.C.
        • Quinn S.
        • Agar M.
        • et al.
        Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction.
        J Pain Symptom Manage. 2015; 49: 814-821
        • Peng X.
        • Wang P.
        • Li S.
        • et al.
        Randomized clinical trial comparing octreotide and scopolamine butylbromide in symptom control of patients with inoperable bowel obstruction due to advanced ovarian cancer.
        World J Surg Oncol. 2015; 13: 50
        • Clark K.
        • Lam L.
        • Currow D.
        Reducing gastric secretions—a role for histamine 2 antagonists or proton pump inhibitors in malignant bowel obstruction?.
        Support Care Cancer. 2009; 17: 1463
      8. al GL et. Recommendations for Bowel Obstruction With Peritoneal Carcinomatosis | EndNote Click.
        (Available at:) (Accessed December 22, 2020)
      9. al TM et. Practice Patterns of Medications for Patients With Malignant Bowel Obstruction Using a Nationwide Claims Database and the Association Between Treatment Outcomes and Concomitant Use of H2-Blockers/Proton Pump Inhibitors and Corticosteroids With Octreotide | EndNote Click.
        (Available at:) (Accessed December 22, 2020)
        • Vayne-Bossert P.
        • Haywood A.
        • Good P.
        • et al.
        Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery).
        Cochrane Database Syst Rev. 2017; 7: CD012002
      10. Gunten ER and CFV. Current concepts in malignant bowel obstruction management | EndNote Click.
        (Available at:) (Accessed December 22, 2020)
        • Feuer D.J.
        • Broadley K.E.
        Systematic review and meta-analysis of corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancers. Systematic Review Steering Committee.
        Ann Oncol. 1999; 10: 1035-1041
      11. Cancer Pain Syndromes- ClinicalKey.
        (Available at:) (Accessed December 22, 2020)
      12. al MTG et. Quality of Cancer Pain Management: An Update of a Systematic Review of Undertreatment of Patients With Cancer | EndNote Click.
        (Available at:) (Accessed December 22, 2020)
        • Sun V.
        • Borneman T.
        • Piper B.
        • et al.
        Barriers to pain assessment and management in cancer survivorship.
        J Cancer Surviv. 2008; 2: 65-71
      13. Available at: Barriers_Final.pdf. Accessed December 22, 2020. https://s3.amazonaws.com/rdcms-iasp/files/production/public/Content/ContentFolders/GlobalYearAgainstPain2/CancerPainFactSheets/Barriers_Final.pdf.

        • Al-Ghabeesh S.H.
        • Bashayreh I.H.
        • Saifan A.R.
        • et al.
        Barriers to Effective Pain Management in Cancer Patients From the Perspective of Patients and Family Caregivers: A Qualitative Study.
        Pain Manag Nurs. 2020; 21: 238-244
        • Chapman E.J.
        • Edwards Z.
        • Boland J.W.
        • et al.
        Practice review: Evidence-based and effective management of pain in patients with advanced cancer.
        Palliat Med. 2020; 34: 444-453
        • Lin J.
        • Hsieh R.-K.
        • Chen J.-S.
        • et al.
        Satisfaction with pain management and impact of pain on quality of life in cancer patients.
        Asia-Pacific J Clin Oncol. 2020; 16: e91-e98
        • Caraceni A.
        • Shkodra M.
        Cancer Pain Assessment and Classification.
        Cancers (Basel). 2019; 11https://doi.org/10.3390/cancers11040510
        • Jaruvongvanich V.
        • Chesta F.
        • Baruah A.
        • et al.
        Palliative treatment for malignant gastrointestinal obstruction with peritoneal carcinomatosis: enteral stenting versus surgery.
        Endosc Int Open. 2020; 8: E1487-E1494
        • Boland P.A.
        • Kelly M.E.
        • Donlon N.E.
        • et al.
        Outcomes following colonic stenting for malignant left-sided bowel obstruction: a systematic review of randomised controlled trials.
        Int J Colorectal Dis. 2019; 34: 1625-1632
        • Paul Olson T.J.
        • Pinkerton C.
        • Brasel K.J.
        • et al.
        Palliative surgery for malignant bowel obstruction from carcinomatosis: a systematic review.
        JAMA Surg. 2014; 149: 383-392
        • Thampy S.
        • Najran P.
        • Mullan D.
        • et al.
        Safety and Efficacy of Venting Gastrostomy in Malignant Bowel Obstruction: A Systematic Review.
        J Palliat Care. 2020; 35: 93-102
        • Chen P.-J.
        • Wang L.
        • Peng Y.-F.
        • et al.
        Surgical intervention for malignant bowel obstruction caused by gastrointestinal malignancies.
        World J Gastrointest Oncol. 2020; 12: 323-331
        • Shariat-Madar B.
        • Jayakrishnan T.T.
        • Gamblin T.C.
        • et al.
        Surgical management of bowel obstruction in patients with peritoneal carcinomatosis.
        J Surg Oncol. 2014; 110: 666-669
      14. al TJPO et. Palliative Surgery for Malignant Bowel Obstruction From Carcinomatosis | EndNote Click.
        (Available at:) (Accessed December 8, 2020)
        • Cousins S.E.
        • Tempest E.
        • Feuer D.J.
        Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer [Systematic Review].
        Cochrane Database Syst Rev. 2016; (CD002764)