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Contributors
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xiii-xvi
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Contents
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xvii-xxv
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Current Management of Small Bowel Obstruction
04 July 2011
Although common, small bowel obstruction (SBO) remains one of the most challenging clinical problems treated by surgeons. Responsible for up to 300,000 hospital admissions every year in North America,...
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Martin Donald Zielinski,
Michael Patrick Bannon
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1-29
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Screening for Colorectal Cancer
Colorectal cancer (CRC) is a leading cause of death from cancer in the United States. In 2010 there are 143,000 new cases of CRC expected with more than 51,000 people dying from the disease. More than...
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Jin He,
Jonathan E. Efron
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31-44
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Varicose Vein: Current Management
04 July 2011
Chronic venous insufficiency can be found in 15% to 20% of the population. The prevalence goes up to 50% if small telangiectasias are included . Venous ulcers are observed in 2% of patients with chron...
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Beejay A. Feliciano,
Michael C. Dalsing
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45-62
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Geographic Variation in Health Care and the Affluence-Poverty Nexus
On March 30, 2010, President Obama signed the Patient Protection and Affordable Care Act into law. While many conceptual themes contributed to its formulation, none was more pervasive than the notion ...
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Richard A. Cooper
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63-82
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Endovascular Approaches to Arteriovenous Fistula
04 July 2011
An arteriovenous fistula (AVF) is any abnormal connection between an artery and a vein that bypasses the normal capillary bed and shunts blood directly to the venous circulation. These abnormal commun...
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Jennifer A. Sexton,
John J. Ricotta
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83-100
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Local and Regional Control in Breast Cancer: Role of Sentinel Node Biopsy
Breast cancer is the most common malignancy and the second most common cause of cancer deaths in American women. The American Cancer Society estimates that 207,090 new cases of invasive breast cancer ...
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Armando E. Giuliano,
Soo Hwa Han
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101-116
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Stem Cells in Acute Liver Failure
13 July 2011
The potential use of stem cells as therapy for failing organ systems is being explored in diverse organ and tissue injury areas. It has been shown that bone marrow-derived stem cells can transdifferen...
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Russell N. Wesson,
Andrew M. Cameron
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117-130
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Is There a Role for Bowel Preparation and Oral or Parenteral Antibiotics In Infection Control in Contemporary Colon Surgery?
Over the past 90 years, colorectal resection has been associated with a progressive increase in safety for what is still a major and frequently performed operation. It has often been stated that the w...
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Susan Galandiuk,
Donald E. Fry,
Hiram C. Polk
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131-140
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Oral Antibiotics to Prevent Surgical Site Infections Following Colon Surgery
For more than two centuries, surgeons have been performing operations on the colon and rectum. This year more than 100,000 colorectal operations will be performed in the United States alone . Despite ...
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Danielle Fritze,
Michael J. Englesbe,
Darrell A. Campbell
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141-153
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Pancreatic Necrosectomy
Acute pancreatitis is a significant cause of morbidity and mortality in the United States, occurring in approximately 44 per 100,000 adults and accounting for more than 200,000 hospital admissions eac...
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Jordan R. Stern,
Jeffrey B. Matthews
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155-176
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The Impact of Health Care Reform on Surgery
I recently had the opportunity to critique the 2010 Affordable Care Act (ACA) . I documented that the 3 pillars of health care delivery—quality, cost, and access—were flawed in the old health care mod...
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Donald D. Trunkey
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177-185
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Glucose Elevations and Outcome in Critically Injured Trauma Patients
04 July 2011
Stress hyperglycemia, defined as a transient plasma glucose level above 200 mg/dL, is associated with adverse outcomes among the critically ill, including increased mortality . Since the landmark stud...
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Joseph J. DuBose,
Thomas M. Scalea
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187-196
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Advances in the Surgical Management of Gastrointestinal Stromal Tumor
Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that typically arises from the alimentary tract . In the past, these tumors were classified as leiomyomas, leiomyosarcomas, or leiomyoblast...
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Umer I. Chaudhry,
Ronald P. DeMatteo
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197-209
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Choledochoceles: Are They Choledochal Cysts?
Choledochal cysts are abnormal dilatations of the biliary tree, generally believed to be congenital in origin. Choledochal cysts are more common in Asian populations (reported incidence of 1 in 1000) ...
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Kathryn M. Ziegler,
Nicholas J. Zyromski
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211-224
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What Does Ulceration of a Melanoma Mean for Prognosis?
04 July 2011
Ulceration is defined pathologically as the absence of intact epithelium overlying a melanoma. In patients with cutaneous melanoma, ulceration of the primary melanoma is a well-known prognostic factor...
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Glenda G. Callender,
Kelly M. McMasters
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225-236
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Influence of Surgical Volume on Operative Failures for Hyperparathyroidism
13 July 2011
Parathyroidectomy is the mainstay of treatment for hyperparathyroidism. Operative intervention in a previously unexplored neck can yield cure rates greater than 95% . However, once a patient has under...
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Barbara Zarebczan,
Herbert Chen
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237-248
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Perioperative Normothermia During Major Surgery: Is It Important?
Perioperative hypothermia (PH), usually defined as a temperature of less than 36.0°C during the perioperative period, can result from anesthesia-induced thermoregulatory inhibition combined with expos...
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Nestor F. Esnaola,
David J. Cole
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249-263
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Surgical Management of Hereditary Nonpolyposis Colorectal Cancer
04 July 2011
Hereditary nonpolyposis colorectal cancer (HNPCC), often called Lynch syndrome, may be described as a hereditary predisposition to developing colorectal and extracolonic cancers. Accounting for approx...
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Matthew F. Kalady
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265-274
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How to Change General Surgery Residency Training
04 July 2011
The training of general surgeons in the United States can trace its roots back to the system introduced by William Stewart Halsted at the Johns Hopkins Hospital, and many of the unique components pers...
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Steven C. Stain
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275-284
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Recent Advances in the Diagnosis and Treatment of Gastrointestinal Carcinoids
Carcinoid tumors were first described by Lubarsch in 1888 . In 1907, Oberndorfer was the first to recognize these tumors as distinct from carcinomas and coined the term, Karzinoide, to describe the c...
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Joseph Valentino,
B. Mark Evers
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285-300
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The Past, Present, and Future of Biomarkers: A Need for Molecular Beacons for the Clinical Management of Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal cancers. It is the fourth leading cause of cancer-related death in the United States . Nearly 40,000 Americans are affected by this dis...
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Jonathan R. Brody,
Agnieszka K. Witkiewicz,
Charles J. Yeo
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301-321
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Robotic-Assisted Major Pancreatic Resection
The first published report of a successful pancreaticoduodenectomy was published by Allen O. Whipple in 1935 . Whipple reported 3 patients who underwent a 2-stage procedure with pancreatic duct ligati...
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H.J. Zeh,
David L. Bartlett,
A. James Moser
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323-340
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Immunotherapy for Metastatic Solid Cancers
04 July 2011
The overwhelming majority of metastatic solid cancers cannot be cured by current systemic chemotherapies. Immunotherapy, a modality able to mediate durable and sometimes complete tumor regression in p...
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Simon Turcotte,
Steven A. Rosenberg
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341-360
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Prophylaxis for Deep Vein Thrombosis and Pulmonary Embolism in the Surgical Patient
Guidelines for venous thromboembolism (VTE) prevention in the surgical patient have been published by the American College of Chest Physicians (ACCP), the American College of Physicians, the American ...
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Taki Galanis,
Walter K. Kraft,
Geno J. Merli
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361-390
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Index
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391-396
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